Abstract:

The immune system is a complex morphofunctional structure responsible for defending the body against internal and external antigens. With the rising prevalence of stress factors, secondary immunodeficiency conditions have become increasingly common. Experimental and clinical data demonstrate that stress-induced immunosuppression leads to distinct morphological alterations in lymphoid organs, particularly the thymus and lymph nodes. This article analyzes histological changes in these organs under stress-induced secondary immunodeficiency, based on theoretical sources and experimental models.