Features of Autoimmune Disorders in Cerebral Paralysis in Children

Abstract

Cerebral palsy (CCP) is a group of persistent movement and posture developmental disorders that cause activity limitations associated with non-progressive damage to the developing brain of the fetus or infant. The prevalence of cerebral palsy is 2-3 cases per 1000 live births, making this disease one of the leading causes of childhood disability worldwide. In recent years, researchers' interest in studying the immunological aspects of cerebral palsy pathogenesis has significantly increased. The accumulated data indicate that immune system dysfunction can play a significant role in both the development and progression of neurological disorders in this disease. Special attention is paid to the study of autoimmune mechanisms that can contribute to the maintenance of the chronic inflammatory process in the nervous tissue and exacerbate existing neurological deficits.