Improvement of the Method of Diagnosis and Treatment of Polypous Rhinosinusitis against the Background of Allergic Rhinitis in Children
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This article presents data on the problem of polypous rhinosinusitis associated with allergic rhinitis in children. Current views on the causes, risk factors, and pathogenic mechanisms of disease development are substantiated. Current concepts and approaches to the diagnosis and treatment of polypous rhinosinusitis associated with allergic rhinitis in children are also discussed.
The aim of the work: to improve the results of diagnosis and treatment of polypous rhinosinusitis against the background of allergic rhinitis in children.
Material and methods: The study included 148 children with polypous rhinosinusitis with and without allergic rhinitis who visited the Bukhara Regional Multidisciplinary Children's Center between 2019 and 2024. The results of diagnosis and treatment were analyzed.
Results: After treatment, all children experienced a significant reduction in their symptoms, which did not impair their quality of life. In particular, the turmeric solution in the second, main group of patients significantly improved their condition compared to the control group. The number of hospital days in patients of the main group was reduced by 2.0±2.5 days compared to patients of the control group.
1. Asmanov, A. I. Modern concepts of allergic rhinitis in children: diagnostics, differential diagnostics, methods of complex therapy / A. I. Asmanov, D. B. Munblit // Russian Bulletin of Perinatology and Pediatrics. - 2011. - V. 56, No. 3. - P. 80-87.
2. Astafieva, N.G. Modern approaches to the treatment of allergic rhinitis / N.G. Astafieva // Russian allergological journal. - 2011. - No. 3. - P. 79-92.
3. Balabolkin, I.I. Allergic diseases in children of early and preschool age: features of pathogenesis and modern approaches to therapy / I.I. Balabolkin // Allergology and immunology in pediatrics. - 2013. - No. 4. - P. 1120.
4. Baranov, A. A. Federal clinical guidelines for the provision of medical care to children with allergic rhinitis / A. A. Baranov, L. S. Namazova-Baranova, R. M. Khaitov, N. I. Ilyina, O. M. Kurbacheva, G. A. Novik, F. I. Petrovsky, E. A. Vishneva, A. A. Alekseeva, L. R. Selimzyanova. - M.: Ministry of Health of the Russian Federation. Union of Pediatricians of Russia. Russian Association of Allergists and Clinical Immunologists, 2015. - 19 p.
5. Eshmolov S.N., Sitnikov I.G., Melnikova I.M. Cytokines TNF-α, IFN-γ, IL-1, IL-4, IL-8 and their role in the immune response to infectious lesions of the central nervous system in children // Children's infections, 2018. Vol. 17, No. 1. P. 17-22.
6. Clinical guidelines of the National Consensus Committee "Polyposis Rhinosinusitis". Moscow, 2012. P. 19.
7. Stepanov E.N. The role of impaired microcirculation of the nasal mucosa in the pathogenesis of various forms of chronic rhinitis // Practical Medicine. 2011. No. 51. P. 11-14.
8. Trushenko N.V. Allergic rhinitis: a modern view on pathogenesis, diagnosis and treatment // Asthma and allergy, 2014. No. 1. Pp. 3-8.].
9. Khaitov M.R., Ilyina N.I., Luss L.V., Babakhin A.A. Mucosal immunity of the respiratory tract and its role in occupational pathologies // Medicine of extreme situations, 2017. No. 3 (61). Pp. 8-24.
10. Chotchaeva A.A., Kolotilina A.I., Korsunsky I.A., Smirnova G.I., Asmanov A.I., Munblit D.B. Allergic rhinitis: approaches to diagnosis and treatment // Russian Medical Journal, 2018. - No. 9. - P. 22-28.
11. Blomme K., Tomassen P., Lapeere H. et al. Prevalence of allergic sensitization versus allergic rhinitis symptoms in an unselected population // Int Arch Allergy Immunol. 2013. Vol. 160(2). P.200‒207.
12. Brożek, J. L. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision / J. L. Brożek, J. Bousquet, I. Agache, A. Agarwal, C. Bachert, S. Bosnic-Anticevich, R. Brignardello-Petersen, G. W. Canonica et al. // J. Allergy Clin. Immunol. - 2017. - Vol. 140, № 4. - Р. 950-958.
13. Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, Cohen N, Cervin A, Douglas R, Gevaert P, Georgalas C, Goossens H, Harvey R, Hellings P, Hopkins C, Jones N, Joos G, Kalogjera L, Kern B, Kowalski M, Price D, Riechelmann H, Schlosser R, Senior B, Thomas M, Toskala E, Voegels R, Wang de Y, Wormald PJ. European position paper on rhinosinusitis and nasal polyps 2012. Rhinol Suppl. 2012;50(23):1-298. doi: 10.2500/ajra.2013.27.3925.
14. Jumayeva Z. J. Qiyosiy jihatdan maktabgacha va inaktab yoshidagi bolalarda allergic rinitning tarqalish xususiyatlari"// Scientific progress- 2020 XII vol.l -C. 44-49.
15. Greiner, A. N. Overview of the treatment of allergic rhinitis and nonallergic rhinopathy / A.N. Greiner, E.O. Meltzer // Proceedings of the American Thoracic Society. - 2011. - Vol. 8, №1. - P. 121-131].
16. Cardell L.O., Olsson P., Andersson M. et al. TOTALL: high cost of allergic rhinitis-a national Swedish population-based questionnaire study // NPJ Prim Care Respir Med. 2016. Vol. 26.P.15082.
17. Scadding G.K., Scadding G., Mirakian R. et al. BSACI guideline for the diagnosis and management of allergic and non-allergic rhinitis // Clinical Experimental Allergy. 2017. Vol. 47. P.856–889.
18. Zhang, Y. Increasing prevalence of allergic rhinitis in China / Y. Zhang, L. Zhang // Allergy, asthma & immunology research. - 2019. - Vol.11, № 2. - Р. 156-169. https://doi.org/10.4168/ aair.2019.11.2.156.
