Of Microbiological Study In Patients With Acute Odontogenic Puscular Inflammatory Diseases

Abstract

Relevance of the study. The prediction of the course of purulent-inflammatory diseases of the maxillofacial region in odontogenic inflammatory diseases is becoming an urgent problem due to its widespread prevalence and the possibility of developing severe complications. According to a number of authors, the relative weight of purulent-inflammatory diseases in the general structure of diseases in maxillofacial hospitals is 60% and has a tendency to increase. According to many researchers, the situation is associated with the following factors. Many works have been devoted to studying the composition of cytokines in the blood and oral fluid of patients with purulent-inflammatory diseases of the maxillofacial region , but the impact of instability on the clinical course and prognosis of the disease has not been fully studied. One of the leading directions in predicting the course of the inflammatory process is the study of gene expression in various factors of immunity. For example, much attention is being paid to searching for associations between cytokine gene variants that determine the stability of immune reactivity.

The purpose of the study. Study of the results of microbiological studies in patients with acute odontogenic purulent-inflammatory diseases.

Results and analyses. In order to determine the composition of the microflora in patients with acute odontogenic purulent-inflammatory diseases and the correlation between the study groups of patients , a microbiological analysis was conducted. When purulent exudate obtained during surgery in 15 1 children with acute odontogenic purulent-inflammatory diseases was studied, it was determined that 62.5 % of the 8 species studied from colony-forming microorganisms were obligate anaerobic bacteria, among which Neisseria spp. , Bacillus sp. , E. cloacae, Proteus spp., Cl. perfringens were detected in the largest number. The concentration of microorganisms in the purulent exudate was 3.71*10 3 from 2.71*10 5 Changed to KOE/ml (colony forming units in 1 ml). Facultative-anaerobic microorganisms consisted mostly of gram-positive species (staphylococci, streptococci, corynebacteria). The concentration of these microorganisms in the pus center varied from 2*10 3 to 1*10 6 KOE/mld, that is, their amount is 10-100 times less than the amount of obligate anaerobes. this information is the domain of most researchers confirms the opinion about the dominance of anaerobic microflora in odontogenic inflammatory diseases.