Integrative Role of the Nervous and Endocrine Systems in Maintaining Homeostasis

nervous system endocrine system homeostasis

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November 29, 2025

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This article explores the complex interaction between the nervous and endocrine systems in maintaining physiological homeostasis in the human body. It explains how both systems detect internal and external changes, transmit signals, and coordinate responses to ensure stable internal conditions. The study highlights the mechanisms of neural and hormonal regulation, the feedback loops involved, and their roles in controlling metabolism, stress response, reproduction, and growth. The integration of these two systems provides a foundation for understanding how the human body maintains equilibrium in the face of environmental fluctuations. The nervous and endocrine systems together form the primary regulatory networks that preserve the constancy of the internal environment despite continuous external changes. This study provides a comprehensive examination of how these two systems interact to sustain physiological equilibrium through neural signaling, hormonal secretion, and feedback regulation. The focus is placed on the dynamic coordination between rapid neural responses and prolonged endocrine adjustments that enable the body to adapt to environmental stressors, temperature variations, and metabolic demands. The integrative functions of the hypothalamus, pituitary gland, and autonomic nervous system are highlighted as central elements in maintaining systemic balance. The findings contribute to a deeper understanding of neuroendocrine integration as a foundation for human health and a target for therapeutic interventions against homeostatic disorders.

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