Biological Properties of Calcium Phosphate, Bone Substitutes, As Well as Experimental Data

Abstract

Report. The standard treatment for bone defects is biological reconstruction using autologous bone, a therapeutic approach that suffers from limitations such as limited amounts. The bone available for collection and the need for further intervention can lead to complications at the donor site. For this reason, synthetic bone substitutes have been developed to reduce or even replace the use of autologous bone as a transplant material. This structured review examines whether calcium phosphates and biologically active glasses (BGS) exhibit improved properties when both embedded bone substitutes are combined into Cap/BG composites. Consequently, it enhances the formation of general biological properties and, in particular, osteogenic properties of cap/BG bone replacement composite materials. Summarizes the latest experimental data for a better understanding. As A Result, BG Falls Into The Caps Of The Current. For this reason, the development, evaluation and production of synthetic bone substitutes that can limit or even replace the use of autologous bone marrow as a material for transplantation are the focus of experimental and clinical orthopedic research.