Psoriasis in the Pediatric Age Group: Disease Phenotypes, Impact on Quality of Life
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Background Psoriasis in children is a heterogeneously-phenotyped, immune-mediated, inflammatory condition with a high psychosocial burden. The optimization of therapeutic strategies depends on the complete knowledge of the phenotypic spectrum as well as its effects on quality-of-life (QoL) where Baseline characteristics were summarized using descriptive statistics and multivariate logistic regression was used to identify predictive factors to adverse outcomes as well as The main aim of the study was to define disease phenotypes, severity, QoL impact, and comorbidity among 120 cases of psoriasis in children, as well as to explain the factors that have an impact on the disease burden through logistic regression analysis where based on A cross sectional study was used, which included children aged between 1 and 18 years old with psoriasis that was clinically proven and found The sample was 54.2 per cent male with a mean age of 10.4 years and a standard deviation of 3.7 in addition to Plaque psoriasis represented the predominant phenotype (65 %), followed by guttate (16.7 %) and pustular (8.3 %) and about Logistic regression revealed a statistically significant relationship between adverse outcome and disease duration (OR= 1.12, p=0.02) and PASI score (OR= 1.20, p=0.001) as well as QoL impact (OR= 1.15, p=0.01) finally paediatric psoriasis has a range of phenotypic expressions and has profound negative impact on quality of life and psychosocial functioning.
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