BASAL GANGLIA

Akramov Abdullo Ahmad o‘g‘li; Do’stmurodova Xosiyatxon Murod kizi; Davranova Malika Alisher kizi; Orifov Jonibek Erkinjon o'g'li; Khakimova Asilabonu Ikrom kizi

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Akramov Abdullo Ahmad o‘g‘li 3rd year of the faculty Pediatrics of Samarkand State Medical University Samarkand,Uzbekistan
Do’stmurodova Xosiyatxon Murod kizi 3rd year of the faculty Pediatrics of Samarkand State Medical University Samarkand,Uzbekistan
Davranova Malika Alisher kizi 3rd year of the faculty Pediatrics of Samarkand State Medical University Samarkand,Uzbekistan
Orifov Jonibek Erkinjon o'g'li 3rd year of the faculty Pediatrics of Samarkand State Medical University Samarkand,Uzbekistan
Khakimova Asilabonu Ikrom kizi 3rd year of the faculty Pediatrics of Samarkand State Medical University Samarkand,Uzbekistan

Vol. 2 No. 1 (2024): International Journal of Pediatrics and Genetics

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February 4, 2024

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This article provides an overview of the anatomical and neurochemical components of the basal ganglia, its historical development, and its involvement in various neurological and psychiatric disorders. The basal ganglia's intricate circuitry, involving the striatum, globus pallidus, substantia nigra, and subthalamic nucleus, is discussed, emphasizing its role in action selection and motor control. The historical journey from early anatomical observations to modern neuroscience techniques is traced, highlighting key contributors and breakthroughs. The article delves into the cortico-basal ganglia-thalamo-cortical loop, the direct and indirect pathways, and the modulation of basal ganglia activity by dopamine. A detailed analysis of the basal ganglia's involvement in Parkinson's disease and Huntington's disease is provided, elucidating the disruptions in circuit connections leading to characteristic motor and cognitive symptoms. Overall, this comprehensive exploration enhances our understanding of the basal ganglia's intricate workings and its significance in health and disease

Akramov Abdullo Ahmad o‘g‘li, Do’stmurodova Xosiyatxon Murod kizi, Davranova Malika Alisher kizi, Orifov Jonibek Erkinjon o’g’li, & Khakimova Asilabonu Ikrom kizi. (2024). BASAL GANGLIA. International Journal of Pediatrics and Genetics , 2(1), 13–20. Retrieved from https://medicaljournals.eu/index.php/IJPG/article/view/147

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Journal title	International Journal of Pediatrics and Genetics
Initials	Int.Jour.Ped.Gen
Frequency	12 issues per year
Prefix DOI	10.xxxxx
Online ISSN	XXXX-XXXX
Editor In Chief	Mehwish Alam []
Publisher	Medical Journals Press

International Journal of Pediatrics and Genetics

BASAL GANGLIA

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