Clinical and Laboratory Changes in Guillain-Barre Syndrome

Abstract

Guillain-Barré syndrome is a severe autoimmune disease affecting the peripheral nervous
system. The most common manifestation is acute tetraparesis, in which the movement of the four limbs
becomes almost impossible. Other movements also cease, including swallowing, the ability to lift the
eyelids, and spontaneous breathing. Nevertheless, the course of the disease is good, and in most cases
it ends with recovery. Transition to a chronic course or relapses are less common. Guillain-Barre
syndrome occurs with the same frequency in all countries, regardless of their level of development -
about 2 cases per 100,000 people, regardless of gender. The disease can affect patients of any age.