SYSTEMS ANALYSIS OF CLINICAL, BIOCHEMICAL, AND NEUROIMAGING PREDICTORS OF NEONATAL HYPOXIC-ISCHEMIC ENCEPHALOPATHY
Keywords:
hypoxic-ischemic encephalopathy, newborns, prognosis, biomarkers, neuroimaging, electroencephalography, neuroprotection, perinatal hypoxia, neonatal neurology, integrative diagnosticsAbstract
Perinatal hypoxic ischemia is caused by impaired cerebral blood supply and oxygenation during childbirth or in the first hours of life, which triggers a cascade of secondary energy failure, oxidative stress, and neuroinflammation. In recent years, significant attention has been devoted to improving methods for the early diagnosis and prognosis of hypoxic-ischemic injuries using clinical scales, neuromonitoring, biomarkers, and neuroimaging.
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