THE ROLE OF METABOLIC SYNDROME IN THE DEVELOPMENT OF CHRONIC BRAIN ISCHEMIA: A SYSTEMATIC REVIEW
Keywords:
Metabolic syndrome, chronic brain ischemia, cognitive impairment, dementia, cardiovascular diseaseAbstract
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities, including central obesity, dyslipidemia, hypertension, and insulin resistance, that increase the risk of cardiovascular disease and type 2 diabetes. Recent evidence suggests that MetS may also play a role in the development of chronic brain ischemia (CBI), a condition characterized by reduced blood flow to the brain that can lead to cognitive impairment and dementia. This review article aims to summarize the current understanding of the relationship between MetS and CBI, highlighting the potential mechanisms through which MetS may contribute to the pathogenesis of CBI. We will also discuss the implications of these findings for the prevention and management of CBI.
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